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# Lumiris aims to boost IVF success rates
- URL: https://med-techinsights.com/lumiris-aims-to-boost-ivf-success-rates/
- Published: 2026-07-22T12:00:00.000Z
- Updated: 2026-10-22T08:31:52.000Z
- Description: Lumiris, a pioneer in reproductive technology, has announced a major breakthrough in fertility science with the discovery of new biomarkers for assessing egg viability. This was made possible by using the company’s METAPHOR platform, marking a successful first application of the technology on human
- Author: Olivia Friett
- Tags: Femtech, News, Research & Development

[**Lumiris**](https://lumiris.tech/?ref=med-techinsights.com)**, a pioneer in reproductive technology, has announced a major breakthrough in fertility science with the discovery of new biomarkers for assessing egg viability.**

This was made possible by using the company’s METAPHOR platform, marking a successful first application of the technology on human oocytes. Presented at the 2026 European Society of Human Reproduction and Embryology (ESHRE) Congress, this first-of-its-kind technology uses a sophisticated, non-invasive metabolic imaging platform to robustly classify the maturation and age-related health of a human oocyte (egg).

The current methods for evaluating egg quality are limited and often invasive. METAPHOR  
establishes a new paradigm. The technology can distinguish between the two fundamental  
processes that determine an egg’s health: maturation and aging. An egg final maturation  
takes about 30 hours, but it carries the metabolic signature of having aged for 30-plus  
years inside a woman’s body. METAPHOR is the first technology that can see and analyze  
the distinct metabolic impact of both the “30 hours and the 30 years,” providing a complete,  
non-invasive assessment of an egg’s health.

For patients, this provides more certainty in fertility procedures like egg freezing. It removes  
the uncertainty from oocyte selection, often the most challenging part of the process,  
offering greater assurance about future possibilities. This is a significant benefit for women  
trying to conceive, particularly those with conditions such as Polycystic Ovary Syndrome  
(PCOS/PMOS), which is linked to lower rates of reproductive success and a higher risk of  
miscarriage. By knowing the quality of the eggs they freeze, women can have greater peace  
of mind about their future. This same clarity enhances the oocyte donation process,  
ensuring patients can be more confident about the quality of donated eggs.

“We are unlocking a new, critical layer of insight for clinicians and patients. By providing a  
clear, non-invasive window into an egg’s metabolic health, METAPHOR represents a pivotal  
step forward in our mission to bring greater clarity and certainty to the fertility journey” says  
Samuel Ojosnegros, co-founder and chief scientific officer at Lumiris.

The research, conducted on 189 human oocytes, demonstrated METAPHOR’s ability to  
provide a detailed, multi-dimensional assessment of an egg’s metabolic status.

Importantly, safety testing on a cohort of 301 mouse oocytes confirmed that the metabolic  
imaging process is developmentally safe.

“’For decades, clinical embryology has relied on visual assessments that only scratch the  
surface of oocyte quality,” says Thomas Freour, Clinical Embryologist and head of the ART  
department at the University Hospital of Nantes-France. “The METAPHOR platform  
represents a significant clinical breakthrough by finally giving us a safe, non-invasive  
window into the metabolic health and cytoplasmic maturity of an egg. By revealing these  
previously hidden physiological markers, we can make far more precise, data-driven  
decisions in the lab, taking the guesswork out of oocyte selection and ultimately offering  
our patients a much clearer path to a successful pregnancy.”

  
The introduction of METAPHOR for oocyte assessment marks a pivotal moment in assisted  
reproductive technology, shifting the focus towards a more personalised and data-driven  
approach to fertility care. Lumiris plans to make this technology available to clinicians and  
patients as soon as clinical tests conclude.